Digestive Mucosa · Histology

Which mucosal hormone, secreted by enteroendocrine cells in the duodenum, stimulates the pancreas to release bicarbonate-rich fluid?

  1. Secretin
  2. Gastrin
  3. Cholecystokinin (CCK)
  4. Ghrelin
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Correct answer: Secretin

Secretin is released in response to acidic chyme entering the duodenum. It acts on the pancreatic duct cells to secrete bicarbonate, which neutralizes the acid to protect the intestinal mucosa.

Difficulty: Medium Question 18 of 20

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