Interstitial Growth · Histology

Which of the following best defines interstitial growth in cartilage?

  1. Growth by depositing new layers of matrix on the outer surface of the cartilage
  2. The gradual conversion of dense connective tissue into hyaline cartilage
  3. The progressive calcification of the territorial matrix surrounding lacunae
  4. Growth from division of chondrocytes within the existing cartilage matrix
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Correct answer: Growth from division of chondrocytes within the existing cartilage matrix

Interstitial growth occurs from within the cartilage mass. It involves the mitotic division of preexisting chondrocytes and the subsequent deposition of new matrix by these daughter cells.

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