Which factor is a major stimulator of chondrocyte mitosis during interstitial growth?
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Correct answer: Insulin-like Growth Factor 1 (IGF-1)
Growth hormone stimulates the production of IGF-1, which acts directly on chondrocytes in the proliferative zone. This signaling pathway is the primary driver of longitudinal skeletal growth during childhood.
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More Interstitial Growth questions
- How does the territorial matrix differ from the interterritorial matrix during interstitial growth?
- In adult humans, interstitial growth is significantly limited because:
- Which of the following is an example of interstitial growth in fibrocartilage?
- What happens to the volume of the lacuna immediately following the mitotic division of a chondrocyte?
- Which organelle would be most prominent in a chondrocyte actively engaged in interstitial growth?
- Interstitial growth is most characteristic of which phase of life?