Osteoblasts · Histology

What is the function of 'Matrix Vesicles' released by osteoblasts?

  1. To transport waste products to the blood
  2. To nucleate the first hydroxyapatite crystals
  3. To signal osteoclasts to begin bone resorption
  4. To act as neurotransmitter storage sites
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Correct answer: To nucleate the first hydroxyapatite crystals

Matrix vesicles are small membrane-bound structures rich in calcium and phosphate-binding proteins. They provide a protected microenvironment where the first crystals of hydroxyapatite can nucleate during the mineralization of osteoid.

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