Osteoblasts · Histology

When an osteoblast becomes completely surrounded by its own secreted matrix and resides in a lacuna, it differentiates into an:

  1. Monocyte
  2. Osteoprogenitor cell
  3. Osteocyte
  4. Bone lining cell
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Correct answer: Osteocyte

Osteocytes are mature bone cells trapped within lacunae. This transition involves a decrease in cytoplasmic volume and organelle content as the cell shifts from matrix production to bone maintenance.

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