Osteoprotegerin (OPG), secreted by osteoblasts, serves what physiological function?
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Correct answer: It blocks RANKL to inhibit osteoclast formation.
OPG is a soluble protein that binds to RANKL, preventing it from interacting with RANK on osteoclast precursors. By secreting OPG, osteoblasts can effectively reduce bone resorption and maintain bone mass.
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