Microscopy Resolution · Histology

Which type of microscopy uses 'optical sectioning' to improve resolution by eliminating out-of-focus light?

  1. Phase-contrast microscopy
  2. Dark-field microscopy
  3. Standard bright-field light microscopy
  4. Confocal scanning laser microscopy
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Correct answer: Confocal scanning laser microscopy

Confocal microscopy uses a pinhole to block light that does not originate from the focal plane. This creates much sharper images with better effective resolution, especially in thicker specimens.

Difficulty: Medium Question 19 of 20

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