Laboratory Bio-Techniques · Zoology

Which condition is essential for successful PCR amplification?

  1. Presence of RNA-based primers
  2. Constant low temperature range
  3. Repeated thermal cycling steps
  4. Absence of magnesium ion cofactor
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Correct answer: Repeated thermal cycling steps

PCR requires repeated cycles of denaturation (high heat to separate strands), annealing (cooling for primer binding), and extension (moderate heat for polymerase synthesis). These thermal cycles enable exponential amplification of the target DNA sequence.

Difficulty: Medium Question 17 of 20

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