Laboratory Bio-Techniques · Zoology

Polyacrylamide gel electrophoresis is especially useful for separating:

  1. Very large DNA molecules only
  2. Proteins and small DNA fragments
  3. Large lipid-protein complexes
  4. Intact whole chromosomes only
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Correct answer: Proteins and small DNA fragments

Polyacrylamide gels have smaller, more uniform pore sizes than agarose gels, allowing high-resolution separation of proteins and small nucleic acid fragments. They are routinely used in SDS-PAGE for protein analysis and in sequencing applications.

Difficulty: Medium Question 18 of 20

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