Animal Stem Cells and Regeneration · Zoology

Which animal is used as a model to study 'lens regeneration', where the iris cells dedifferentiate and transform into a new lens?

  1. Laboratory mouse
  2. Common fruit fly
  3. Red-spotted newt
  4. Nematode roundworm
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Correct answer: Red-spotted newt

Newts (and some other salamanders) exhibit Wolffian regeneration. After lens removal, pigmented epithelial cells of the dorsal iris lose their pigment, proliferate, and transdifferentiate into a new functional crystalline lens.

Difficulty: Medium Question 19 of 20

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