Induced Pluripotent Stem Cells (iPSCs) are typically created by 'reprogramming' adult somatic cells with which set of transcription factors?
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Correct answer: Oct4, Sox2, Klf4, and c-Myc
Known as the Yamanaka factors, these four transcription factors are sufficient to revert a specialized adult cell back into a pluripotent state. This technology allows for the creation of patient-specific stem cells without using embryos.
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