Animal Stem Cells and Regeneration · Zoology

In the context of limb regeneration in salamanders (Urodeles), what is the mass of undifferentiated, proliferating cells that forms at the site of amputation?

  1. Callus (cartilaginous repair tissue)
  2. Blastema
  3. Primitive streak
  4. Apical ectodermal ridge
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Correct answer: Blastema

A blastema is a pool of mesenchymal-like cells formed by the dedifferentiation of local tissues at the wound site. It serves as the progenitor source for the replacement of bones, muscles, and nerves in the regenerated limb.

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