Cytoskeleton and Its Filaments · Zoology

Desmosomes and hemidesmosomes anchor cells to each other and the extracellular matrix by connecting to which cytoskeletal element?

  1. Microtubules
  2. Actin microfilaments
  3. Intermediate filaments
  4. Cortical stress fibers
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Correct answer: Intermediate filaments

Intermediate filaments, such as keratins in epithelial cells, are anchored to the plasma membrane at desmosomes (linking adjacent cells) and hemidesmosomes (linking cells to the basal lamina). This cytoskeletal attachment provides epithelial tissues with the tensile strength to resist mechanical stress.

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