The antigen-binding site of an antibody is formed by:
Show answer and explanation
Correct answer: Variable regions of both heavy and light chains
The antigen-binding site (paratope) is created by the hypervariable (complementarity-determining) regions within the variable domains of both the heavy and light chains. These regions confer exquisite antibody specificity.
Keep practicing
More Immunoglobulins and Antigens questions
- Which class of immunoglobulin is most abundant in human serum?
- Which immunoglobulin is the first to be produced during a primary immune response?
- Which immunoglobulin is mainly found in mucosal secretions such as saliva and milk?
- The Fc region of an antibody is primarily involved in:
- Which immunoglobulin class is associated with allergic reactions?
- An antigen is defined as a substance that: