Thermoregulation and Body Fluids · USMLE Step 1

A patient with SIADH develops hyponatremia. Which change is most expected in intracellular fluid volume?

  1. Decreased ICF volume
  2. Increased ICF volume
  3. No change in ICF volume
  4. Shift of sodium into cells
Show answer and explanation

Correct answer: Increased ICF volume

Hyponatremia lowers plasma osmolality, causing water to shift into cells. This increases intracellular volume.

Difficulty: Medium Question 5 of 20

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