What is the main mechanism by which neurotransmitter action is terminated in the synaptic cleft?
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Correct answer: Diffusion, reuptake by neurons or glia, and enzymatic breakdown
Signal termination typically involves removal of neurotransmitter from the cleft by diffusion, uptake by presynaptic neuron or glial cells, and/or enzymatic degradation — not by receptors degrading the transmitter.
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