Endocrine regulation · USMLE Step 1

Which of the following pairs appropriately illustrates a hormone and its primary peripheral effect?

  1. TSH → increased insulin release
  2. ACTH → increased cortisol secretion
  3. GnRH → increased thyroid hormone production
  4. ADH → increased glucagon secretion
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Correct answer: ACTH → increased cortisol secretion

ACTH stimulates the adrenal cortex to secrete cortisol (a glucocorticoid), which is the primary peripheral effect in the HPA axis response.

Difficulty: Medium Question 10 of 23

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