Which of the following best describes how sex steroids regulate the HPG axis in adults under normal conditions?
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Correct answer: Negative feedback of sex steroids on hypothalamus and pituitary
Gonadal sex steroids (e.g., testosterone, estrogen) exert negative feedback on the hypothalamus and anterior pituitary to suppress GnRH and LH/FSH secretion, thereby regulating the HPG axis.
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