In the regulation of the (HPG axis), continuous (non-pulsatile) administration of (GnRH) leads to which of the following outcomes?
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Correct answer: Decreased LH and FSH release from pituitary
Continuous (non-pulsatile) GnRH leads to downregulation of GnRH receptors in the pituitary and paradoxically reduces LH and FSH release, suppressing gonadal function — a principle used clinically for GnRH agonist therapy.
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