Drug Classes and Mechanisms · USMLE Step 1

Which drug class reduces LDL cholesterol by increasing clearance of LDL via upregulated LDL receptors?

  1. Bile acid sequestrants
  2. Statins
  3. Fibrates
  4. Loop diuretics
Show answer and explanation

Correct answer: Statins

Statins decrease cholesterol synthesis in the liver, leading to upregulation of LDL receptors and increased clearance of LDL from the circulation.

Difficulty: Medium Question 7 of 19

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