Drug Classes and Mechanisms · USMLE Step 1

A drug that decreases peripheral vascular resistance and lowers afterload but exerts little effect on cardiac output likely belongs to which class?

  1. Non-dihydropyridine calcium channel blocker
  2. Dihydropyridine calcium channel blocker
  3. Beta-blocker
  4. ACE inhibitor
Show answer and explanation

Correct answer: Dihydropyridine calcium channel blocker

Dihydropyridine calcium channel blockers (e.g., amlodipine) predominantly act on vascular smooth muscle to cause vasodilation, reducing afterload with minimal effect on cardiac output.

Difficulty: Medium Question 8 of 19

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