Antimicrobials and Resistance · USMLE Step 1

A man receiving rifampin notices orange discoloration of body fluids. What additional effect should be monitored?

  1. Bone marrow suppression
  2. Inhibition of CYP450 enzymes
  3. Induction of CYP450 enzymes
  4. Severe nephrotoxicity
Show answer and explanation

Correct answer: Induction of CYP450 enzymes

Rifampin is a strong CYP450 inducer and may decrease levels of many drugs.

Difficulty: Medium Question 10 of 20

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