Antimicrobials and Resistance · USMLE Step 1

A patient with gonorrhea is treated with ceftriaxone. Which resistance mechanism could compromise treatment?

  1. Altered porin proteins
  2. Efflux pumps
  3. β-lactamase production
  4. Methylation of 23S rRNA
Show answer and explanation

Correct answer: Altered porin proteins

Neisseria gonorrhoeae often develops resistance through porin mutations that prevent antibiotic entry.

Difficulty: Medium Question 14 of 20

Practice all 20 Antimicrobials and Resistance questions

Keep practicing

More Antimicrobials and Resistance questions