Which of the following syndromes is an example of a non-Mendelian, imprinting or uniparental disomy disorder rather than classic autosomal or chromosomal abnormality?
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Correct answer: Prader–Willi syndrome
Prader–Willi syndrome typically arises from lack of paternal allele expression on chromosome 15 — either by paternal deletion or maternal uniparental disomy — an imprinting disorder distinct from classic Mendelian inheritance.
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