Multisystem: Shock, Sepsis and Metabolic Syndromes · USMLE Step 1

A patient with septic shock is treated with norepinephrine. Which effect does this medication primarily provide?

  1. Bradycardia with peripheral vasodilation
  2. Increased heart rate with minimal vasoconstriction
  3. Vasoconstriction preserving coronary perfusion
  4. Selective pulmonary artery vasodilation
Show answer and explanation

Correct answer: Vasoconstriction preserving coronary perfusion

Norepinephrine causes potent α1-mediated vasoconstriction, helping restore systemic vascular resistance. It supports blood pressure in septic shock.

Difficulty: Medium Question 5 of 19

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