Host immune response · USMLE Step 1

Type I interferons (IFN-α, IFN-β) help control viral infections by which mechanism?

  1. Stimulating mucosal IgA production
  2. Inhibiting viral protein synthesis
  3. Increasing neutrophil chemotaxis
  4. Activating eosinophil degranulation
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Correct answer: Inhibiting viral protein synthesis

Type I interferons induce an antiviral state by blocking protein synthesis in neighboring cells. This limits viral spread.

Difficulty: Medium Question 12 of 20

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