Bacteria: Structure and Pathogenesis · USMLE Step 1

In Gram-positive bacteria, what is the function of teichoic acids in the cell wall?

  1. Serve as a secreted endotoxin
  2. Stabilize the bacterial outer membrane
  3. Provide negative charge and rigidity
  4. Act as porins for nutrient uptake
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Correct answer: Provide negative charge and rigidity

Teichoic acids are anionic polymers in Gram-positive cell walls that help maintain cell wall rigidity and contribute to the overall negative charge of the bacterial surface.

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