Cell-cell junctions · USMLE Step 1

Which of the following functions is NOT typically associated with cell–cell junctions in epithelial tissue?

  1. Establishing cell polarity by restricting lateral diffusion of membrane proteins
  2. Allowing free diffusion of large proteins between adjacent cell cytoplasms
  3. Providing mechanical adhesion between cells
  4. Controlling paracellular permeability between adjacent cells
Show answer and explanation

Correct answer: Allowing free diffusion of large proteins between adjacent cell cytoplasms

Cell–cell junctions like tight junctions and gap junctions regulate permeability and selective communication; they generally do not allow free diffusion of large proteins between adjacent cell cytoplasms — only small molecules/ions can pass via gap junctions.

Difficulty: Medium Question 8 of 20

Practice all 20 Cell-cell junctions questions

Keep practicing

More Cell-cell junctions questions