Which inheritance pattern would you suspect if all children — male and female — of an affected male are affected?
Show answer and explanation
Correct answer: X-linked dominant
If an affected male transmits the trait to all his children (both sexes), this suggests X-linked dominant inheritance, since he passes his mutant X chromosome to all daughters and mutant Y (non-trait) to sons only, but daughters receive the trait, and if trait is fully penetrant, all children may be affected depending on pattern.
Keep practicing
More Pedigree analysis questions
- Which feature on a pedigree would argue for autosomal rather than X-linked inheritance when both sexes show roughly equal affected frequenc…
- In pedigree analysis with a rare autosomal recessive trait, what is the chance that two carrier parents will have an unaffected child who i…
- In a pedigree chart, a filled square usually represents what?
- Which mode of inheritance is most consistent with a trait that appears in every generation and affects both sexes equally?
- If two unaffected parents have an affected child, which mode of inheritance is most likely?
- In a pedigree for an X-linked recessive disease, which of the following patterns is most suggestive?