Pedigree analysis · USMLE Step 1

Which mode of inheritance is most consistent with a trait that appears in every generation and affects both sexes equally?

  1. Autosomal recessive
  2. Autosomal dominant
  3. X-linked recessive
  4. Mitochondrial
Show answer and explanation

Correct answer: Autosomal dominant

Autosomal dominant traits typically appear in every generation and affect males and females equally, because a single mutant allele on an autosome is enough for expression.

Difficulty: Medium Question 2 of 19

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