Cell Signalling and Receptor Mechanisms · USMLE Step 1

Which of the following is NOT one of the three major classes of cell-surface receptors involved in signal transduction?

  1. G-protein–coupled receptors (GPCRs)
  2. Ligand-gated ion channels
  3. Enzyme-linked receptors
  4. Mitochondrial inner-membrane receptors
Show answer and explanation

Correct answer: Mitochondrial inner-membrane receptors

The three canonical cell-surface receptor classes are GPCRs, ligand-gated ion channels, and enzyme-linked receptors; mitochondrial inner-membrane receptors are not a standard category.

Difficulty: Medium Question 7 of 22

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