Membrane Transport Mechanisms · Physiology

Why is facilitated diffusion of glucose via a transporter more efficient than simple diffusion, despite both being passive processes?

  1. Because glucose is lipid-soluble and diffuses rapidly through the bilayer
  2. Because carrier proteins ferry large polar glucose across the hydrophobic bilayer
  3. Because glucose crosses inside transport vesicles during facilitated diffusion
  4. Because facilitated diffusion is powered directly by ATP hydrolysis
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Correct answer: Because carrier proteins ferry large polar glucose across the hydrophobic bilayer

Glucose is large and polar, unable to dissolve in the hydrophobic bilayer; facilitated diffusion uses specific transporters to move glucose across the membrane down its concentration gradient — something not possible via simple diffusion.

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