Pituitary and Thyroid Physiology · Physiology

Which of the following would occur if the hypothalamic-pituitary stalk were surgically severed?

  1. Decrease in every anterior pituitary hormone level
  2. Increase in prolactin, drop in other anterior hormones
  3. Increase in ADH alongside a decrease in oxytocin release
  4. Decrease in prolactin with a rise in TSH secretion
Show answer and explanation

Correct answer: Increase in prolactin, drop in other anterior hormones

Most anterior pituitary hormones rely on hypothalamic 'releasing' hormones, so their levels drop. Prolactin, however, is tonically inhibited by dopamine; removing this inhibition leads to an increase in Prolactin levels.

Difficulty: Medium Question 26 of 40

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