Menstrual Cycle and Spermatogenesis · Physiology

The 'blood-testis barrier' is primarily formed by which of the following?

  1. Basement membrane of the seminiferous tubule
  2. Tight junctions between Sertoli cells
  3. Endothelial cells of the testicular capillaries
  4. The tunica albuginea
Show answer and explanation

Correct answer: Tight junctions between Sertoli cells

Tight junctions between adjacent Sertoli cells create a physical barrier. This prevents the blood-borne substances and immune cells from reaching the germ cells, which are genetically distinct and would be attacked as 'foreign'.

Difficulty: Medium Question 38 of 40

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