Adrenal and Pancreas Hormones · Physiology

How does cortisol affect the immune system?

  1. It boosts the production of pro-inflammatory cytokines
  2. It enhances the activity and proliferation of T-lymphocytes
  3. It inhibits histamine release and reduces capillary permeability
  4. It promotes the migration of white blood cells to injured tissue
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Correct answer: It inhibits histamine release and reduces capillary permeability

Cortisol is globally immunosuppressive and anti-inflammatory. It inhibits phospholipase A2 (reducing prostaglandins) and stabilizes lysosomal membranes, making it useful in treating allergic and autoimmune reactions.

Difficulty: Medium Question 16 of 40

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