Adrenal and Pancreas Hormones · Physiology

The 'C-peptide' is a useful clinical marker for which of the following?

  1. Alpha cell function
  2. Exogenous insulin administration
  3. Endogenous insulin production
  4. Adrenal medulla exhaustion
Show answer and explanation

Correct answer: Endogenous insulin production

Proinsulin is cleaved into insulin and C-peptide in a 1:1 ratio before secretion. Measuring C-peptide allows clinicians to distinguish between insulin made by the patient's pancreas and injected (exogenous) insulin.

Difficulty: Medium Question 19 of 40

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