Platelets and Clotting Disorders · Physiology

Which platelet receptor is responsible for binding fibrinogen during platelet aggregation?

  1. GPIb-IX-V complex
  2. GPIIb/IIIa
  3. GPVI collagen receptor
  4. P-selectin adhesion molecule
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Correct answer: GPIIb/IIIa

The GPIIb/IIIa receptor binds fibrinogen, allowing platelets to cross-link with each other. This interaction is crucial for platelet aggregation.

Difficulty: Medium Question 5 of 20

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