Platelets and Clotting Disorders · Physiology

Platelet adhesion to damaged endothelium is primarily mediated by:

  1. Circulating fibrinogen
  2. Von Willebrand factor
  3. Prothrombin complex
  4. Antithrombin III cofactor
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Correct answer: Von Willebrand factor

Von Willebrand factor bridges platelets to exposed collagen at the injury site. This step is essential for primary hemostasis.

Difficulty: Medium Question 4 of 20

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