Platelets and Clotting Disorders · Physiology

The intrinsic pathway of coagulation is initiated by activation of:

  1. Factor VII
  2. Factor XII
  3. Factor X
  4. Factor V
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Correct answer: Factor XII

The intrinsic pathway begins with activation of factor XII upon contact with negatively charged surfaces. This pathway is assessed by the aPTT test.

Difficulty: Medium Question 7 of 20

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