Beta-2 Agonists · Pharmacology

A patient using an Albuterol inhaler frequently complains of 'shaking hands.' What is the pharmacological basis for this tremor?

  1. Stimulation of Beta-1 receptors in the heart
  2. Stimulation of Beta-2 receptors in skeletal muscle
  3. Blockade of nicotinic receptors at the neuromuscular junction
  4. Central nervous system depression
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Correct answer: Stimulation of Beta-2 receptors in skeletal muscle

Skeletal muscle contains Beta-2 receptors that, when stimulated, can lead to fine muscle tremors. This is a common systemic side effect of Beta-2 agonists, even when administered via inhalation.

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