Loop Diuretics · Pharmacology

A patient taking high-dose Furosemide along with an aminoglycoside antibiotic is at a significantly increased risk for which toxicity?

  1. Nephrotoxicity
  2. Ototoxicity
  3. Hepatotoxicity
  4. Cardiotoxicity
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Correct answer: Ototoxicity

Both loop diuretics and aminoglycosides can cause damage to the hair cells in the cochlea. When used together, their ototoxic effects are synergistic, potentially leading to permanent hearing loss.

Difficulty: Medium Question 5 of 20

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