Monoclonal Antibodies · Pharmacology

Tocilizumab is a monoclonal antibody that blocks the receptor for which pro-inflammatory cytokine?

  1. IL-1
  2. IL-2
  3. IL-6
  4. IL-12
Show answer and explanation

Correct answer: IL-6

Tocilizumab binds to both soluble and membrane-bound IL-6 receptors. IL-6 plays a key role in the pathogenesis of rheumatoid arthritis and cytokine release syndrome (CRS), making its blockade clinically valuable.

Difficulty: Medium Question 16 of 20

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