Basiliximab is used in organ transplantation to prevent acute rejection by targeting which molecule?
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Correct answer: CD25 (alpha subunit of IL-2 receptor) on activated T-cells
Basiliximab is an IL-2 receptor antagonist. By binding to the CD25 subunit, it prevents IL-2 from stimulating the proliferation of activated T-cells, which is a critical step in the acute rejection of a transplanted organ.
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