Which immunosuppressant inhibits the enzyme inosine monophosphate dehydrogenase (IMPDH)?
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Correct answer: Mycophenolate Mofetil
Mycophenolate Mofetil is a prodrug that is converted to mycophenolic acid, which inhibits IMPDH. This enzyme is critical for the de novo synthesis of guanosine nucleotides, which lymphocytes rely on for proliferation.
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