Which signaling molecule is primarily associated with the activation of the Gq protein pathway?
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Correct answer: Inositol trisphosphate (IP3) and diacylglycerol (DAG)
Activation of $G_q$ proteins stimulates phospholipase C, which cleaves membrane phosphoinositides into IP3 and DAG. These second messengers then lead to increased intracellular calcium and protein kinase C activation.
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