Which enzyme is responsible for the hydrolysis of the local anesthetic Procaine and the neuromuscular blocker Succinylcholine in the plasma?
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Correct answer: Butyrylcholinesterase
Butyrylcholinesterase, also called pseudocholinesterase, is synthesized in the liver and secreted into the plasma. It rapidly hydrolyzes ester-containing drugs, terminating their action within minutes unless the patient has a genetic deficiency in this enzyme.
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