Which of the following describes the 'Volume of Distribution' (Vd) of a drug?
Show answer and explanation
Correct answer: A theoretical volume relating total drug in the body to plasma concentration
Vd is a pharmacokinetic parameter used to quantify the extent of drug distribution. It represents the volume required to contain the total amount of drug at the same concentration as that found in the plasma.
Keep practicing
More Drug Distribution questions
- Which plasma protein is the most significant binder for acidic drugs like Warfarin and Salicylates?
- A drug with an extremely high Volume of Distribution (Vd > 40 L/70kg) typically indicates that:
- Which anatomical barrier is characterized by tight junctions between endothelial cells and a lack of fenestrations, limiting drug entry int…
- What is the clinical significance of 'Displacement' in the context of plasma protein binding?
- Which of the following factors would decrease the distribution of a drug to a specific organ?
- Basic drugs, such as Lidocaine and Propranolol, primarily bind to which plasma protein, especially during acute inflammation?