To ensure maximal efficacy, when should a delayed-release oral PPI typically be administered?
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Correct answer: 30 to 60 minutes before the first meal of the day
PPIs should be taken before a meal so that peak drug levels coincide with the maximal activation of proton pumps by food. Since they only inhibit active pumps, pre-prandial dosing is essential for optimal acid suppression.
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More Proton Pump Inhibitors questions
- Which of the following PPIs is the S-enantiomer of Omeprazole and typically exhibits slower hepatic clearance?
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- Which of the following is an FDA-approved clinical indication for PPIs?