H2 Blockers · Pharmacology

H2 blockers are particularly effective at inhibiting which type of gastric acid secretion?

  1. Nocturnal and basal acid secretion
  2. Meal-stimulated acid secretion
  3. Gastrin-stimulated acid secretion only
  4. Cephalic phase acid secretion only
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Correct answer: Nocturnal and basal acid secretion

Nocturnal acid secretion is largely dependent on histamine. Therefore, H2RAs are highly effective at controlling acid production during the night, even if they are less effective at controlling food-induced secretion.

Difficulty: Medium Question 7 of 20

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