Clinical Trials · Pharmacology

A 'Single-Blind' study is most commonly used when:

  1. The drug is too dangerous for double-blinding
  2. Blinding the investigator is impossible or unethical (e.g., surgery vs. medication)
  3. The study is in Phase IV
  4. The sample size is very small
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Correct answer: Blinding the investigator is impossible or unethical (e.g., surgery vs. medication)

In single-blind studies, only the patient is unaware of the treatment. This is often necessary when the investigator must know the treatment to perform a procedure or monitor specific safety parameters.

Difficulty: Medium Question 11 of 20

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